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- Title
Relationship Between Blood Lipid Levels and Mortality in Hospitalized COVID-19 Patients.
- Authors
Aydın, Sidar Ş; Aksakal, Emrah; Aydınyılmaz, Faruk; Gülcü, Oktay; Saraç, İbrahim; Kalkan, Kamuran; Aydemir, Selim; Doğan, Remziye; Aksu, Uğur; Tanboğa, İbrahim H
- Abstract
People with comorbid conditions are at increased risk of developing severe/fatal coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between lipid levels and mortality in patients hospitalized for COVID-19 infection. In this retrospective study, we collected the details of 5274 COVID-19 patients who were diagnosed using the polymerase chain reaction and/or computed tomography and were hospitalized between March and November 2020. Patients (n = 4118) whose blood lipid levels were checked within the first 24 h after hospitalization were included in the study. Multivariable cox proportional hazards regression was used to assess the relationship between lipid variables such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) and death. There was a statistically significant association between LDL-C, HDL-C, and TG levels and the risk of death (P =.002, <.001, and.035, respectively). Low and high LDL-C, low HDL-C, and high TG levels were negatively associated with COVID-19-related mortality. Blood lipid levels may be useful predictors of mortality in COVID-19 patients.
- Subjects
HDL cholesterol; TRIGLYCERIDES; LENGTH of stay in hospitals; HOSPITAL patients; COVID-19; MORTALITY; RETROSPECTIVE studies; LDL cholesterol; RISK assessment; POLYMERASE chain reaction; COMPUTED tomography; LIPIDS
- Publication
Angiology, 2022, Vol 73, Issue 8, p724
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/00033197211072346