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- Title
The Unruptured Intracranial Aneurysm Treatment Score as a predictor of aneurysm growth or rupture.
- Authors
Molenberg, Rob; Aalbers, Marlien W.; Mazuri, Aryan; Luijckx, Gert Jan; Metzemaekers, Jan D. M.; Groen, Rob J. M.; Uyttenboogaart, Maarten; van Dijk, J. Marc C.
- Abstract
Background and purpose: The Unruptured Intracranial Aneurysm Treatment Score (UIATS) was built to harmonize the treatment decision making on unruptured intracranial aneurysms. Therefore, it may also function as a predictor of aneurysm progression. In this study, we aimed to assess the validity of the UIATS model to identify aneurysms at risk of growth or rupture during follow‐up. Methods: We calculated the UIATS for a consecutive series of conservatively treated unruptured intracranial aneurysms, included in our prospectively kept neurovascular database. Computed tomography angiography and/or magnetic resonance angiography imaging at baseline and during follow‐up was analyzed to detect aneurysm growth. We defined rupture as a cerebrospinal fluid or computed tomography–proven subarachnoid hemorrhage. We calculated the area under the receiver operator curve, sensitivity, and specificity, to determine the performance of the UIATS model. Results: We included 214 consecutive patients with 277 unruptured intracranial aneurysms. Aneurysms were followed for a median period of 1.3 years (range 0.3–11.7 years). During follow‐up, 17 aneurysms enlarged (6.1%), and two aneurysms ruptured (0.7%). The UIATS model showed a sensitivity of 80% and a specificity of 44%. The area under the receiver operator curve was 0.62 (95% confidence interval 0.46–0.79). Conclusions: Our observational study involving consecutive patients with an unruptured intracranial aneurysm showed poor performance of the UIATS model to predict aneurysm growth or rupture during follow‐up.
- Subjects
INTRACRANIAL aneurysms; MAGNETIC resonance angiography; ANEURYSMS; MAGNETIC resonance imaging; SUBARACHNOID hemorrhage
- Publication
European Journal of Neurology, 2021, Vol 28, Issue 3, p837
- ISSN
1351-5101
- Publication type
Article
- DOI
10.1111/ene.14636