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- Title
Multifunctional Magnetic Nanomedicine Drug Delivery and Imaging‐Based Diagnostic Systems.
- Authors
Aslam, Hira; Shukrullah, Shazia; Naz, Muhammad Yasin; Fatima, Hareem; Ullah, Sami; Al‐Sehemi, Abdullah G.
- Abstract
Magnetically guided drug transportation is a technique in which magnetic pharmaceutical transporters in organisms are controlled by applied magnetic forces to deliver drugs to the desired location. Different magnetic drug delivery systems (MDDSs) are developed to treat a variety of illnesses, particularly cancer and neurological disorders. However, a unique magnetic setup is required in each application for an effective magnetically guided drug aiming to direct the drug‐carrying nanocarriers to the intended area. The current and future perspectives of MDDS are investigated in this study by considering their biological functions, deliverable efficiency, complexity, and the nature of the externally applied magnetic field. Despite the fact that MDDSs have low cytotoxicity, regulated magneto reactivity, extended circulation lifespan, and high surface stability, very few clinical studies have been conducted to date in order to achieve optimized therapeutic efficacy before entering the market. In recent studies, the development of novel magnetic medication transporting carriers is preferred over direct magnetic medication administration. Better functional magnetic targeting technologies are required for such breakthroughs to enter clinical trials. Because MDDSs are unlikely to work in all clinical situations, more focused research is needed to replace or improve the strategy for treating multiple illnesses.
- Subjects
NANOMEDICINE; MAGNETISM; SURFACE stability; MAGNETIC fields; MAGNETIC control; DRUG delivery systems
- Publication
Particle & Particle Systems Characterization, 2021, Vol 38, Issue 12, p1
- ISSN
0934-0866
- Publication type
Article
- DOI
10.1002/ppsc.202100179