Four new oleanane saponins, lobelioidosides A-D ( 1- 4, resp.), all endowed with 16-oxo and a 23-OH group, as well as with a 13,28-epoxy bridge as a common moiety, have been isolated from the 75% EtOH extract of the whole plant of Lysimachia lobelioides. Their structures were elucidated on the bases of MS, 1H- and 13C-NMR, HMQC, HMBC, and 1H,1H-COSY data analysis.