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- Title
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.
- Authors
Khelashvili, George; Dorff, Kevin; Jufang Shan; Camacho-Artacho, Marta; Skrabanek, Lucy; Vroling, Bas; Bouvier, Michel; Devi, Lakshmi A.; George, Susan R.; Javitch, Jonathan A.; Lohse, Martin J.; Milligan, Graeme; Neubig, Richard R.; Palczewski, Krzysztof; Parmentier, Marc; Pin, Jean-Philippe; Vriend, Gerrit; Campagne, Fabien; Filizola, Marta
- Abstract
Summary: Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.
- Subjects
G proteins; COMPUTERS in biology; INFORMATION storage &; retrieval systems; OLIGOMERS; DIMERS
- Publication
Bioinformatics, 2010, Vol 26, Issue 14, p1804
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btq264