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- Title
The Predictive Value of C-reactive Protein to Albumin Ratio to Detect Contrast-induced Acute Kidney Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
- Authors
Karakurt, Ahmet
- Abstract
Aim: The present study aims to investigate the predictive value of the peak C-reactive protein to reduced albumin ratio (CAR) in the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (pPCI). MaTerial and Method: Two hundred and ten patients with non-ST and ST-elevation AMI undergoing pPCI were recorded. Renal function parameters and highest CAO values of the patients after pPCI were recorded from the patient files. The patient population was divided intothe low-, mid-, and high-CAR tertiles (all n=70) after their CAR values were ranked from least to greatest. ReSults: Eighty-nine (42.38%) patients developed CI-AKI. The absolute increase in serum creatinine (sCr) was significantly higher in patients in the high-CAR tertile (0.31, interquartile range (IQR): 1.925-0.555) than in the low-CAR (0.2, IQR: 0.118-0.27) and mid-CAR tertiles (0.2, IQR: 0.13-0.33; p<0.001). The area under the curve of CAR was0.689 (95% CI: 0.614-0.763; p<0.001) in the receiver operating characteristic analysis. After adjusting for other risk factors of CI-AKI, CAR remained predictors of the development of CI-AKI (OR: 1.345, 95% CI: 1.009-1.794, p=0.043). Conclusion: The elevated CAR value is independent predictors in the development of CI-AKI in patients with AMI undergoing pPCI. In this patient group, the elevated CAR value after pPKG may alert us to more improve CI-AKI.
- Subjects
ACUTE kidney failure; MYOCARDIAL infarction; PERCUTANEOUS coronary intervention; C-reactive protein; ALBUMINS
- Publication
Kafkas Journal of Medical Sciences / Kafkas Tıp Bilimleri Dergisi, 2021, Vol 11, Issue 2, p231
- ISSN
2146-2631
- Publication type
Article
- DOI
10.5505/kjms.2021.13285