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- Title
Ketone body oxidation: glycogen‐sparing yet glucose‐dependent?
- Authors
Petrick, Heather L.; Pinckaers, Philippe J. M.; Brunetta, Henver S.
- Abstract
Kadir et al. ([1]) examined HB-glucose TCA cycle interactions under the hypothesis that glucose metabolism would be necessary to support HB oxidation due to the ability of pyruvate to be converted into oxaloacetate and, ultimately, replenish the TCA cycle. Keywords: beta-hydroxybutyrate; glucose; glycogen; heart; ketone bodies; muscle EN beta-hydroxybutyrate glucose glycogen heart ketone bodies muscle 2237 2239 3 06/19/23 20230615 NES 230615 Since the competitive relationship between fatty acid and carbohydrate metabolism was demonstrated by Randle 60 years ago, the interplay among substrates is now understood to be more dynamic than initially thought. Ketone body oxidation: glycogen-sparing yet glucose-dependent?.
- Subjects
KETONES; FLAVIN adenine dinucleotide; OXIDATION; FATTY acid oxidation; CARBOHYDRATE metabolism; NAD (Coenzyme); FATTY acid analysis
- Publication
Journal of Physiology, 2023, Vol 601, Issue 12, p2237
- ISSN
0022-3751
- Publication type
Article
- DOI
10.1113/JP284561