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- Title
Five new limonoids isolated from Walsura robusta.
- Authors
Hou, Li; Mei, Cui-Xuan; Yuan, Chun-Mao; Tang, Gui-Hua; Chen, Duo-Zhi; Zhao, Qing; He, Hong-Ping; Cao, Ming-Ming; Hao, Xiao-Jiang
- Abstract
Five new toosendanin limonoids with highly oxidative furan ring walsurobustones A-D (1–4), and one new furan ring degraded limonoid walsurobustone E (5) together with one known compound toonapubesic acid B (6) were isolated from the leaves of Walsura robusta. Their structures were elucidated by NMR and MS data. Especially, the absolute configuration of toonapubesic acid B (6) was confirmed by X-ray diffraction study. Compounds 1–6 exhibited good cytotoxicity against the cancer cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480.
- Subjects
LIMONOIDS; X-ray diffraction; CELL lines; CANCER cells
- Publication
Natural Products & Bioprospecting, 2023, Vol 13, Issue 1, p1
- ISSN
2192-2209
- Publication type
Article
- DOI
10.1007/s13659-023-00371-6