We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Long-term Efficacy Against Fleas (Ctenocephalides felis, Bouché 1835) of Monthly Topical Treatments with Fipronil Based Spot on Formulations Compared to a Flumethrin/Imidacloprid Impregnated Collar on Dogs Subjected to Regular Water Exposure.
- Authors
Halos, Lénaïg; Fourie, Josephus; Bester, Ina; Pollmeier, Matthias; Beugnet, Frédéric
- Abstract
The objective of this study was to compare the long term efficacy against fleas (Ctenocephalides felis) of repeated monthly topical treatments with Fipronil based spot-on products (Certifect® followed by Frontline® Combo, both Merial) to the efficacy of a flumethrin/imidacloprid impregnated collar (Seresto®, Bayer Animal Health) on dogs exposed to simulated rain. The two fipronil based spot-on products contain the same amounts of fipronil and (S)-methoprene, and are registered in Europe with a one-month flea control claim while the flumethrin/ imidacloprid impregnated collar has a flea efficacy claim of 7 to 8 months. Eighteen dogs were followed during an 8 months period. Six dogs remained untreated, 6 dogs were fitted with the imidacloprid/flumethrin collar on Day 0, and 6 dogs were treated monthly for 3 months with fipronil-based formulations starting on Day 120 (Certifect® on Days 120 and 150 followed by Frontline® Combo on Days 181 and 210). Flea infestations comprising 100 C. felis each were performed twice a month starting on Day 134 and repeated through Day 231. Dogs were showered with water for 1 minute at fort-nightly intervals starting the week after each treatment throughout the study. The efficacy of monthly administered fipronil-based spot on products was not impacted by the simulated rain as confirmed by reductions in C. felis counts between 96% to 100% at all timepoints. The efficacy of the flumethrin/ imidacloprid impregnated collar was markedly impacted by the simulated rain with reductions in C. felis counts of between 31.7% to 64.8% versus control following challenge in months 4-8. The efficacy of the fipronil-based spot-on products was significantly higher (p<0.05) than the efficacy observed with the flumethrin/imidacloprid impregnated collar at all challenge times.
- Subjects
FLEAS; FIPRONIL
- Publication
International Journal of Applied Research in Veterinary Medicine, 2014, Vol 12, Issue 2, p101
- ISSN
1559-4602
- Publication type
Article