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- Title
Renal tubular functions in children with primary nocturnal enuresis.
- Authors
Kalman, Süleyman; Sakallioglu, Onur; Kesik, Vural; Gök, Faysal
- Abstract
Introduction: The etiology of primary nocturnal enuresis (PNE) is multifactorial. The effects of genetic and hormonal factors, sleep disorders, and bladder dysfunction have been claimed. The other factors include increased urine production at night and impairment of the circadian rhythm of antidiuretichormone. Aim: To investigate renal tubular functions in children with PNE. Methods: Forty patients with PNE were included in the study. Urine density, FENa, FEK and TRP were analyzed in day time and nighttime urine. Results: The mean nighttime urine density was 1020.12±7.38 and the mean day time urine density was 1013.20±7.11 (p<0.05). There was no significant difference between daytime and nighttim evalues of FENa (0.50±0.48 vs. 0.38±0.33), FEK (2.78±1.04 vs. 2.76±1.52) and TRP (88.5±2.4 vs 86.7±2.8) (p>0.05). Conclusion: Urinedensity in children with PNE was lower at night. However, there was no difference in of FENa, FEK and TRP. Further studies are needed in order to investigate renal tubular functions in children with PNE.
- Publication
Medical Bulletin of Haseki / Haseki Tip Bulteni, 2012, Vol 50, Issue 1, p10
- ISSN
1302-0072
- Publication type
Journal Article