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- Title
Increased Cases of Acute Polyneuropathy in COVID-19 Pandemic: What Awaits Neurologists?
- Authors
ELİAÇIK, Sinan; UYSAL TAN, Funda; KOCAGÜL ÇELİKBAŞ, Aysel
- Abstract
Objective: Severe acute respiratory syndrome coronavirus disease-2019 (COVID-19) primarily affects the respiratory system but central and peripheral neurological manifestations have been increasingly recognized and reported. Our aim is to shed light on the relationship between COVID-19 and polyneuropathy. Material and Methods: The study consisted of patients with acute polyneuropathy that developed after the COVID-19 infection. All patients were confirmed serologically with polymerase chain reaction positivity. In 16 patients, acute polyneuropathy was diagnosed with an electrophysiological, laboratory findings and neurological examination. All patients underwent etiological studies to exclude possible causes of polyneuropathy. Results: The average age of the patients was 64.3 (29-83) years; most cases were female (13 vs 3). The interval between the onset of symptoms of COVID-19 and the first symptoms of acute polyneuropathy ranged from 11 to 63 (mean: 21.5) days. On electroneuromyography, there was acute motor-sensory axonal neuropathy in 8 patients, 6 patients had acute motor axonal neuropathy and 2 patients had acute inflammatory demyelinating polyneuropathy findings. Five patients accepted lumbar puncture; on analysis of the cerebrospinal fluid (CSF), 2 patient had normal protein level and the others showed an albuminocytological dissociation, increased protein in the CSF without increase in cell count, characteristic of the Gullain-Barré syndrome (GBS). Conclusion: This article; indicates the awareness of the possible causal association between acute polyneuropathy and COVID-19, and recommends long-term follow-up of COVID-19 patients for neurologic complications.
- Subjects
CEREBROSPINAL fluid examination; COVID-19; POLYNEUROPATHIES; GUILLAIN-Barre syndrome; POLYMERASE chain reaction; ELECTROMYOGRAPHY; COVID-19 pandemic
- Publication
Journal of Physical Medicine & Rehabilitation Sciences, 2022, Vol 25, Issue 3, p346
- ISSN
1309-3843
- Publication type
Article
- DOI
10.31609/jpmrs.2022-90845