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- Title
Myelofibrosis and Systemic Lupus erythematosus: Reversal of Fibrosis with High-Dose Corticosteroid Therapy.
- Authors
Inoue, Yasushi; Matsubara, Atsushi; Okuya, Shigeru; Okafuji, Koichiro; Kaku, Kohei; Kaneko, Toshio
- Abstract
A case of myelofibrosis in association with systemic lupus erythematosus (SLE) is reported. Acute thrombocytopenia and a bleeding tendency developed in a 24-year-old woman with SLE. Bone marrow aspiration was unsuccessful due to myelofibrosis. Pulse therapy with methylprednisolone reversed both thrombocytopenia and myelofibrosis. A review of the literature revealed that the coexistence of SLE and myelofibrosis is a rare occurrence. Only 7 cases, to our knowledge, have ever been reported in detail. The present case is the 3rd in which myelofibrosis was reversed by corticosteroids. Copyright © 1992 S. Karger AG, Basel
- Publication
Acta Haematologica, 1992, Vol 88, Issue 1, p32
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000204592