We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Isodicentric X Chromosome in Myeloproliferative Disorders.
- Authors
Temperani, Paola; Zucchini, Patrizia; Emilia, Giovanni; Sacchi, Stefano; Selleri, Licia; Torelli, Umberto
- Abstract
Two further cases of acquired isodicentric (X)(q13) chromosome in patients with myeloproliferative disorders are reported. One patient had a primary myelofibrosis and the other a chronic myelogenous leukemia. DNA replication study demonstrated that both abnormal X chromosomes were late replicating in all cells examined. The inactive condition of idic(X)(q13) seems to be indicative of a selective advantage for a cell carrying this alteration. Copyright © 1989 S. Karger AG, Basel
- Publication
Acta Haematologica, 1989, Vol 81, Issue 3, p152
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000205549