We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Haemoglobin Lepore<sub>Baltimore</sub> in a Spanish Family.
- Authors
Villegas, A.; Espinós, D.; Alvarez-Sala, J.L.; Calero, F.; Valverde, F.; Robb, L.; Lehmann, H.
- Abstract
Description of the clinical, haematological and biochemical aspects of a new family with heterozygous haemoglobin LeporeBaitimore·Of the 6 members affected, 4 were totally asymptomatic. All of them showed morphologic features of heterozygous β-thalassaemia. The levels of haemoglobin Lepore ranged from 12.2 to 15% (mean value: 13.7 ± 1.1 %). The analysis of the primary structure of the haemoglobin shows that crossing over takes place between amino acid 50 of the δ-chain and amino acid 86 of the β-chain. This is the third family, to our knowledge, with haemoglobin LeporeBaitimore so far described. Copyright © 1983 S. Karger AG, Basel
- Publication
Acta Haematologica, 1983, Vol 69, Issue 3, p192
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000206888