We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Paraproteinemic Variety of Pure Red Cell Aplasia.
- Authors
Resegotti, L.; Dolci, C.; Palestro, G.; Peschle, C.
- Abstract
A case of adult pure red cell aplasia (PRCA) with a serum IgG inhibitor to erythropoiesis and an IgG λ M component is presented. The study of lymphocyte populations revealed a slight but definite decrease of E and EA rosettes, with dissociation between E rosettes and PHA blastic transformation of blood lymphocytes and increase of membrane IgM-bearing lymphocytes. The relationship between PRCA and paraproteinemia is discussed: it is suggested that the serum M component may derive from an immunological unbalance between T and B lymphocytes. Since a survey of the literature reveals 5 similar cases, it is suggested that paraproteinemia may be the hallmark of a particular variety of chronic PRCA 'type 1'. Copyright © 1978 S. Karger AG, Basel
- Publication
Acta Haematologica, 1978, Vol 60, Issue 4, p227
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000207718