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- Title
Evaluación de un gel antiséptico de aplicación intravaginal para pacientes con infecciones cervicovaginales multitratadas.
- Authors
Montesinos-Peña, Nardia Eneida; Hernández-Valencia, Marcelino; Delgado-Enciso, Iván; Herrera-Leal, Alberto; Paz-Michel, Brenda Astrid
- Abstract
OBJECTIVE: To evaluate the efficacy and safety of an intravaginal antiseptic gel, made of electrolyzed water, against bacterial, yeast, parasitic and mixed cervical infections, and to control typical symptoms in multi-treated patients. MATERIALS AND METHODS: Clinical study, comparative with conventional treatment, two arms, multicentric, randomized, with dose escalation carried out in patients attended between May 2017 and May 2018 in the gynecology and obstetrics service of the Hospital General de Ecatepec La Américas, in the Estado de Mexico and the Centro Hospitalario Unión, of Colima. Control group: conventional scheme, antibiotic-antifungal (7 days); Experimental groups, antiseptic gel for 3, 5 or 10 days. Monitoring of vaginal pH, etiologic agent and symptoms. RESULTS: 62 multi-treated patients (18-42 years old) were enrolled, presenting bacterial vaginosis 25/62, yeast infection 10/62, trichomoniasis 6/62 or mixed infection 21/62; bacteria and yeast). Treatment with antiseptic gel during 5 or 10 days eradicated etiological agent, respectively in 14/15 patients and 18/20 patients; control treatment did it in 8/14 patients (p = 0.021, p = 0.026, respectively). Additionally, gel treatment for 5 or 10 days was 3 times more effective than control treatment to eradicate the infection, control symptoms and to normalize vaginal pH. CONCLUSIONS: Intravaginal antiseptic gel (5-10 days) was almost 3 times more effective than conventional therapy (antibiotics/antimycotics) against multi-treated cervical infections; as well as useful to control typical symptoms and well tolerated.
- Subjects
ANTISEPTICS; VAGINAL contraceptives; BACTERIAL vaginitis; GYNECOLOGY; TRICHOMONIASIS
- Publication
Ginecología y Obstetricia de México, 2019, Vol 87, Issue 7, p454
- ISSN
0300-9041
- Publication type
Article
- DOI
10.24245/gom.v87i7.3009