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- Title
Colestasis intrahepática del embarazo: reporte de un caso y revisión de la bibliografía.
- Authors
González-Blanco, Rafael; Sofía Mortara-Gómez, Águeda; Martínez-Uribe, Alfonso; Arias-Loza, Rosa; Sanginés-Martínez, Augusto
- Abstract
Intrahepatic cholestasis of pregnancy has a prevalence of 1/1000 to 1/10000. Its etiology is multifactorial, involving genetic an hormonal factors, associated with adverse perinatal and obstetric outcomes. Report the case of patient 25 years old, with 32 weeks of gestation, which presents severe pruritus, jaundice, altered liver function tests and lipid profile, with presumptive diagnosis of intrahepatic cholestasis of pregnancy. Making weekly monitoring analytical biochemistry, test of fetal wellbeing, symptomatic management, with abdominal pregnancy termination at 35 weeks, for lack of clinical improvement, increase in metabolic disorders and intrauterine growth restriction, after induction of fetal lung maturity, with good obstetric and perinatal outcome. Definitive diagnosis by liver biopsy.
- Subjects
CHOLESTASIS; PREGNANCY complications; ITCHING; BILE acids; URSODEOXYCHOLIC acid; FETAL monitoring; LIVER biopsy; DIAGNOSIS
- Publication
Ginecología y Obstetricia de México, 2013, Vol 81, Issue 11, p652
- ISSN
0300-9041
- Publication type
Case Study