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- Title
Prevalence of preterm birth and risk factors associated with it at different gestational ages.
- Authors
Yi-Jie Zhang; Yan Zhu; Li Zhu; Cheng-Qiu Lu; Chao Chen; Lin Yuan
- Abstract
Objectives: To investigate the prevalence of preterm birth (PTB) and the risk factors for different gestational age subgroups of preterm birth in China. Methods: We carried out a descriptive cross-sectional study encompassing all singleton live births (24+0 to 41+6 weeks) with completed data in 23 provinces in China from 2010 to 2017 during investigation period. We compared both the preterm group (24+0 to 36+6 weeks) and preterm subgroups (>32 weeks, 32+0 to 33+6 weeks, and 34+0 to 36+6 weeks) with the term group (37+0 to 41+6 weeks). We collected information on maternal and fetal characteristics from medical records. Logistic regression was use. Results: The prevalence of PTB was 7.4% (15,833/215,254) in singleton births. After adjusting for maternal age, parity, and potential risk factors in univariate analysis, the high-risk factors for PTB at >32 weeks were placental abruption (aOR=41.52; 95% CI, 25.89-66.58), placenta previa (aOR=40.04; 95% CI, 32.00-50.09), chorioamnionitis (aOR=11.06; 95% CI, 8.738-14.02), and hypertension disorders in pregnancy (HDP) (aOR=3.564; 95% CI, 2.9304.335). Intrahepatic cholestasis of pregnancy (ICP) was significantly associated with PTB at 34-36 weeks (aOR=5.763; 95% CI, 5.049-6.577), particularly with spontaneous PTB (a0R=10.04; 95% CI, 8.79-11.47). Gestational diabetes mellitus (GDM) was significantly associated with PTB at 34-36 weeks only (aOR=1.156; 95% CI, 1.054-1.267). Conclusion: Placental abruption, placenta previa, chorioamnionitis, and HDP were more predictive of early PTB; GDM and ICP were more predictive of late PTB.
- Subjects
CHINA; PREMATURE labor; ABRUPTIO placentae; CHORIOAMNIONITIS; GESTATIONAL diabetes; GESTATIONAL age; HYPERTENSION in pregnancy; PLACENTA praevia
- Publication
Saudi Medical Journal, 2022, Vol 43, Issue 6, p599
- ISSN
0379-5284
- Publication type
Article
- DOI
10.15537/smj.2022.43.6.20220210