We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis and antibacterial activity of the sulfonamide based schiff base and its transition metal (II) complexes.
- Authors
Khan, Mehak Nawaz; Khan, Abdul Majeed; Ullah, Hamid; Hussain, Sajjad; Khan Khattak, Azim
- Abstract
A Schiff base 3 has been synthesized by equimolar reaction (condensation) of sulfonamide i.e. sulfamethoxypyridazine 1 and substituted aromatic aldehyde i.e. 2-Hydroxy-1-Napthalene aldehyde 2. The synthesized Schiff base 3 and its Metal (II) complexes were characterized by its physical, analytical (CHN analysis) and spectral (UV & IR) analysis. The Staphylococcus aureus and Escherichia coli bacterial strains were used for antibacterial activity of Sulfamethoxypyridazine 1, its Schiff base 3 and its transition metal (II) complexes 4-8. All of them showed varied levels of activity.
- Subjects
SCHIFF bases; ADVANCED glycation end-products; ANTIBACTERIAL agents; SULFALENE; ESCHERICHIA coli
- Publication
Pakistan Journal of Pharmaceutical Sciences, 2018, Vol 31, Issue 1, p103
- ISSN
1011-601X
- Publication type
Article