We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Gold nanoparticles application to the treatment of brain dysfunctions related to metabolic diseases: evidence from experimental studies.
- Authors
Silveira, Paulo César Lock; Rodrigues, Matheus Scarpatto; Gelain, Daniel Pens; de Oliveira, Jade
- Abstract
Nanotechnology is an emerging and expanding technology worldwide. The manipulation of materials on a nanometric scale generates new products with unique properties called nanomaterials. Due to its significant expansion, nanotechnology has been applied in several fields of study, including developing materials for biomedical applications, i.e., nanomedicine. The use of nanomaterials, including nanoparticles, in nanomedicine, is promising and has been associated with pharmacokinetics, bioavailability, and therapeutic advantages. In this regard, it is worth mentioning the Gold Nanoparticles (AuNPs). AuNPs' biomedical application is extensively investigated due to their high biocompatibility, simple preparation, catalytic, and redox properties. Experimental studies have pointed out critical therapeutic actions related to AuNPs in different pathophysiological contexts, mainly due to their anti-inflammatory and antioxidant effects. Thus, in this review, we will discuss the main experimental findings related to the therapeutic properties of AuNPs in metabolic, neurodegenerative diseases, and ultimately brain dysfunctions related to metabolic diseases.
- Subjects
METABOLIC disorders; NANOMEDICINE; TECHNOLOGICAL innovations; BIOMEDICAL materials; NANOSTRUCTURED materials; NEURODEGENERATION; SELF-healing materials
- Publication
Metabolic Brain Disease, 2023, Vol 38, Issue 1, p123
- ISSN
0885-7490
- Publication type
Article
- DOI
10.1007/s11011-022-00929-2