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- Title
Syncope paradox in the outcome of patients with pulmonary thromboembolism: short-term and midterm outcome.
- Authors
Seyyedi, Seyyed‐reza; Jenab, Yaser; Tokaldany, Masoumeh Lotfi; Shirani, Shapoor; Sadeghian, Saeed; Jalali, Arash
- Abstract
Background and Aim We compare the early and midterm outcomes of pulmonary thromboembolism ( PTE) in patients with and without syncope in our single-center registry. Method Between December 2006 and May 2013, 351 consecutive patients (mean age = 60.21 ± 16.91 years, 55.3% male) with confirmed acute symptomatic PTE were divided in with and without syncope groups. Groups were compared in terms of the effect of syncope on 30-day mortality and adverse events, and mortality in a median follow-up time of 16.9 months. Results From 351 patients, 39 (11.1%) had syncope and 312 (88.9%) did not. Syncope group had less frequently chest pain (30.8% vs 51.4%; P value = 0.015). Also, the rates of 30-day adverse events and mortality were 12.8% and 5.1% for the group with syncope, and 14.4% and 10.3% for the group without syncope, respectively, with no significant difference. At follow up, 65 patients died and mortality was 18.5% for 351 patients (5.1% in the group with syncope and 20.2% for the other group). After adjustment for confounding factors, the effect of syncope on 30-day adverse events and mortality remained non-significant and on the midterm mortality was significant, showing that the presence of syncope was associated with lower midterm mortality ( P value = 0.038). Conclusion Among PTE patients in our registry, 11.1% presented with syncope. Relationship between syncope and 30-day adverse events and mortality remained non-significant after adjustments for other factors. However, in midterm follow up, patients with syncope were significantly at decreased risk of mortality compared to those without syncope.
- Subjects
MORTALITY; THROMBOEMBOLISM; PROGNOSIS; SYNCOPE; PARADOX
- Publication
Clinical Respiratory Journal, 2016, Vol 10, Issue 1, p90
- ISSN
1752-6981
- Publication type
Article
- DOI
10.1111/crj.12183