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- Title
FIBROMYALGIA SYNDROME: REVIEW OF THE EPIDEMIOLOGY AND MECHANISMS INVOLVED.
- Authors
Smith, Howard
- Abstract
Although fibromyalgia syndrome (FMS) affects approximately 3 million to 8 million Americans and has a significant negative impact on daily functioning and quality of life, there is no consensus among clinicians on the cause of FMS, its treatments, or even whether it is a "real" illness. Some clinicians recognize it as a disorder of central and peripheral pain processing, whereas others believe it to be a somatic syndrome with a strong psychological and/or emotional component. To help bridge the divide, this article reviews the clinical features and evaluation of FMS, discusses the crucial role of central sensitization, and examines evidence for several mechanisms thought to contribute to the syndrome. These include peripheral, spinal, and supraspinal mechanisms associated with abnormalities of sensory processing.
- Subjects
EPIDEMIOLOGY; FIBROMYALGIA; AMERICANS; QUALITY of life; PAIN; MEDICAL personnel; DISEASES
- Publication
Johns Hopkins Advanced Studies in Medicine, 2009, Vol 9, Issue 4, p108
- ISSN
1530-3004
- Publication type
Article