We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: a case-control study.
- Authors
Vineis, P; Miligi, L; Crosignani, P; Davico, L; Fontana, A; Masala, G; Nanni, O; Ramazzotti, V; Rodella, S; Stagnaro, E; Tumino, R; Viganò, C; Vindigni, C; Costantini, A S
- Abstract
In a population-based case-control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10 years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1-16.2). We propose that late infection is a proliferative stimulus for B-cells.
- Subjects
ITALY; LYMPHOCYTIC leukemia; MYELOID leukemia; ADENOIDECTOMY; LEUKEMIA; SURGICAL complications; CASE-control method; CELL division; TONSILLECTOMY; EPSTEIN-Barr virus; EPSTEIN-Barr virus diseases; DISEASE complications
- Publication
British Journal of Cancer, 2003, Vol 88, Issue 1, p47
- ISSN
0007-0920
- Publication type
journal article
- DOI
10.1038/sj.bjc.6600689