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- Title
Mining the infant gut microbiota for therapeutic targets against atopic disease.
- Authors
Boutin, Rozlyn C. T.; Sbihi, Hind; Dsouza, Melissa; Malhotra, Raunaq; Petersen, Charisse; Dai, Darlene; Sears, Malcolm R.; Moraes, Theo J.; Becker, Allan B.; Azad, Meghan B.; Mandhane, Piush J.; Subbarao, Padmaja; Finlay, B. Brett; Turvey, Stuart E.
- Abstract
Keywords: atopic dermatitis; atopy; food sensitization; live biotherapeutic product; microbiota EN atopic dermatitis atopy food sensitization live biotherapeutic product microbiota 1 4 4 07/29/20 20200801 NES 200801 Abbreviations LBP live biotherapeutic product rDNA ribosomal deoxyribonucleic acid SCFA short-chain fatty acid Forty percent of the world's population is sensitized to at least one environmental allergen, and atopic diseases such as asthma, atopic dermatitis, and food allergy are among the most frequent health challenges faced by children today. Specifically, increased bacterial diversity (as quantified by the Shannon -diversity index) was associated with protection against allergic sensitization (atopy), wheeze, AW, FS, and AD (Figure 1A and Figure E4).
- Subjects
WHEEZE; ATOPY; GUT microbiome; ETIOLOGY of diseases; DISEASES; INFANTS; FOOD allergy
- Publication
Allergy, 2020, Vol 75, Issue 8, p1
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.14244