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- Title
Pathophysiology and Treatment of Pulmonary Arterial Hypertension.
- Authors
Fukumoto, Yoshihiro
- Abstract
This document is an editorial from the International Journal of Molecular Sciences that discusses the pathophysiology and treatment of pulmonary arterial hypertension (PAH). PAH is a rare and severe condition characterized by remodeling and obstruction of pulmonary microvessels, leading to increased pulmonary vascular resistance and right ventricular failure. The document also addresses chronic thromboembolic pulmonary hypertension (CTEPH), which can develop from pulmonary artery obstructions due to organized fibrotic clots. The editorial highlights recent research on cellular pathogenesis mechanisms and potential treatment options for PAH and CTEPH. Despite advancements in pulmonary vasodilators, there is still a need for treatments that target the underlying causes of these conditions.
- Subjects
PULMONARY arterial hypertension; PATHOLOGICAL physiology; BRAIN natriuretic factor; PULMONARY circulation; PULMONARY artery diseases; VENTRICULAR remodeling; VASCULAR remodeling
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 2, p1166
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25021166