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- Title
Uncovering the Lipid Web: Discovering the Multifaceted Roles of Lipids in Human Diseases and Therapeutic Opportunities.
- Authors
Pandey, Manoj Kumar
- Abstract
Future research efforts should focus on unraveling the complex mechanisms underlying lipid dysregulation, exploring lipid-lowering strategies, and identifying novel therapeutic targets to combat lipid-related disorders. From the protective effects of HDL cholesterol in cardiovascular disease to the implications of lipid droplets in cancer growth and survival, neuroinflammation, and neurodegenerative diseases, the importance of lipid metabolism cannot be overstated. Furthermore, the exploration of lipid profiles and lipid-mediated mechanisms in various diseases, such as malaria-associated cerebral malaria [[86]] and leptin-mediated regulation of lipid metabolism in breast cancer [[71]], provides valuable insights into disease pathogenesis and potential diagnostic markers. By understanding the specific alterations in lipid metabolism associated with different diseases, studies can develop targeted interventions to restore lipid homeostasis and mitigate disease progression.
- Subjects
ADIPOGENESIS; LIPIDS; ETHER lipids; LIPOLYSIS; SARS-CoV-2; STEROL regulatory element-binding proteins
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 17, p13223
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms241713223