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- Title
Emergence of blaNDM-5-producing Escherichia coli ST410 in Companion Dogs Treated with Meropenem.
- Authors
Oh, J. Y.; Sum, S.; Song, W. K.; Chae, J. C.; Park, H. M.
- Abstract
Carbapenem-resistant Escherichia coli (CRE) with a multidrug resistant phenotype was isolated from four clinically ill dogs treated with meropenem in different local animal hospitals between 2017 and 2019. IncX3-type plasmids of ca. 46 kb in size carrying blaNDM-5 were present in all CRE strains and their transconjugants. High genetic similarity (>90%) by PFGE analysis was observed among the CRE strains, which were identified as ST410.To the best of our knowledge, blaNDM-5-producing E. coli ST410 clones are emerging sporadically in companion dogs treated with meropenem. The spread of Enterobacteriaceae harboring the NDM-5 gene in companion animals can pose a threat to public health; therefore, extensive monitoring in veterinary hospitals using carbapenem and careful antibiotic use are crucial for managing and monitoring these resistant strains.
- Subjects
ESCHERICHIA coli; CARBAPENEMS; DOGS; PETS; VETERINARY hospitals; MEROPENEM; ENTEROBACTERIACEAE; ANTIBIOTICS
- Publication
Pakistan Veterinary Journal, 2020, Vol 40, Issue 4, p534
- ISSN
0253-8318
- Publication type
Article
- DOI
10.29261/pakvetj/2020.073