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- Title
An individualised tapering protocol reduces opioid use 1 year after spine surgery: A randomised controlled trial of patients with preoperative opioid use.
- Authors
Uhrbrand, Peter Gaarsdal; Rasmussen, Mikkel Mylius; Haroutounian, Simon; Nikolajsen, Lone
- Abstract
Background: Persistent opioid use following surgery is common especially in patients with preoperative opioid use. This study aims to determine the long‐term effect of an individualised opioid tapering plan versus standard of care in patients with a preoperative opioid use undergoing spine surgery at Aarhus University Hospital, Denmark. Methods: This is the 1‐year follow‐up of a prospective, single‐centre, randomised trial of 110 patients who underwent elective spine surgery for degenerative disease. The intervention was an individualised tapering plan at discharge and telephone counselling 1 week after discharge, compared to standard of care. Postoperative outcomes after 1 year include opioid use, reasons for opioid use and pain intensity. Results: The overall response rate to the 1‐year follow‐up questionnaire was 94% (intervention group 52/55 patients and control group 51/55 patients). Forty‐two patients (proportion = 0.81, 95% CI 0.67–0.89) in the intervention group compared to 31 (0.61, 95% CI 0.47–0.73; p =.026) patients in the control group succeeded in tapering to zero 1 year after discharge (p =.026). One patient (0.02, 95% CI 0.01–0.13) in the intervention group compared to seven patients (0.14, 95% CI 0.07–0.26) in the control group were unable to taper to their preoperative dose 1 year after discharge (p =.025). Back/neck and radicular pain intensity was similar between study groups. Conclusion: These results suggest that an individualised tapering plan at discharge combined with telephone counselling 1 week after discharge can reduce opioid use 1 year after spine surgery.
- Subjects
DENMARK; SPINAL surgery; RANDOMIZED controlled trials; HOTLINES (Counseling); OPIOIDS; DISCHARGE planning; NECK pain
- Publication
Acta Anaesthesiologica Scandinavica, 2023, Vol 67, Issue 8, p1085
- ISSN
0001-5172
- Publication type
Article
- DOI
10.1111/aas.14266