We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Evaluation of Goal-Directed Antibiotics Prophylaxis Applied Via Rectal Swab Before Transrectal Ultrasound-Guided Prostate Biopsy.
- Authors
Akgüneş, Ebubekir; Aydın, Mustafa; Görgün, Selim; Günal, Özgür; Bitkin, Alper; Keleş, Mevlüt; Atilla, Mustafa Kemal; Irkilata, Lokman
- Abstract
Objective: This study examined bacterial resistance to antibiotics administered for prophylaxis in rectal swaps taken before biopsy in patients who underwent transrectal ultrasound-guided prostate biopsy (TRUS). Materials and Methods: This prospective study evaluated 251 patients who underwent TRUS in the clinic between January 2015 and December 2016. The patients were administered ciprofloxacin one day before the biopsy, the day of the biopsy, and five days after the biopsy. Urinalysis of patients was performed before biopsy and those with active infection were excluded from the study. Swap samples of patients were taken from the rectal mucosa before the biopsy. These samples were cultivated in blood agar and EMB growth medium. E. coli and Klebsiella reproductions were assessed. Antibiogram tests were studied in terms of resistance/sensitivity after identifying these bacterial subgroups. Results: In the comparison of resistance and sensitivity of microorganism-independent antibiotics, the highest resistance was detected in amoxicillin (70%). The resistance to ciprofloxacin was 41.8%. The highest sensitivity was detected for fosfomycin (97.6%) and ceftazidime (91.6%). Extended spectrum beta-lactamase (ESBL) positivity was detected based on the bacterial species (p=0.001). The study found that ESBL positivity did not affect prostatitis development (p=0.447). The study also found that prostatitis development was not based on ciprofloxacin sensitivity/resistance in the rectal swap (p=0.803). A total of 105 patients showed resistance to ciprofloxacin. Prostatitis development was observed in 5 (4.8%) of these patients. Prostatitis development was observed in 11 (4.3%) of 251 patients. Conclusion: According to the results of this study, antibiotic prophylaxis for rectal swab culture taken before TRUS does not affect prostatitis development after the biopsy. Although rectal swap guided goal-oriented prophylaxis does not reduce infective complications, it may be beneficial so as not to administer additional antibiotics to patients.
- Subjects
PROSTATE biopsy; PREVENTIVE medicine; CIPROFLOXACIN; AMOXICILLIN; PROSTATITIS
- Publication
Bulletin of Urooncology, 2022, Vol 21, Issue 2, p52
- ISSN
2667-4610
- Publication type
Article
- DOI
10.4274/uob.galenos.2022.2021.11.2