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- Title
Use of Hemogram Parameters in the Differentiation of Benign Thyroid Nodules and Thyroid Papillary Carcinoma Cases.
- Authors
Özdemir, Dursun Burak; Özdemir, Ümit; Karayiğit, Ahmet; Dizen, Hayrettin; Ünal, Bülent
- Abstract
Introduction: We aimed to compare red cell distribution width (RDW), mean platelet volume (MPV), and some other laboratory parameters in patients with papillary thyroid carcinoma (PTC) or benign thyroid nodule (BTN). Methods: A total of 365 cases (186 with PTC and 179 with BTN) who underwent lobectomy or bilateral total thyroidectomy were included in the study. The patients were divided into two groups, PTC and BTN, according to histopathological diagnosis. Results: 76.4% of the patients were female and the mean age was 54.94±13.76 years. The median RDW value was 13.3% (12.7-13.9) in the PTC group and 13.2% (12.7-14.2%) in the BTN group. Mean MPV value was 10.28±1.20 fL in the PTC group and 10.26±1.07 fL in the BTN group. The groups were similar in terms of MPV and RDW values (p=0.477 and p=0.883, respectively). Thyroid gland size and detected nodule sizes were significantly greater in the BTN group compared to the PTC group (p<0.001 for all). Discussion and Conclusion: Complete blood count results, including RDW and MPV, were found to have no clinical value in distinguishing between PTC and BTN.
- Subjects
THYROIDECTOMY; THYROID gland tumors; PAPILLARY carcinoma; DIFFERENTIAL diagnosis; RETROSPECTIVE studies; ACQUISITION of data; SURGERY; PATIENTS; MANN Whitney U Test; FISHER exact test; COMPARATIVE studies; CANCER patients; T-test (Statistics); PEARSON correlation (Statistics); MEDICAL records; DESCRIPTIVE statistics; CHI-squared test; HISTOLOGICAL techniques; ERYTHROCYTES; BLOOD cell count; DATA analysis software; RECEIVER operating characteristic curves; SENSITIVITY &; specificity (Statistics); MEAN platelet volume; THYROID gland
- Publication
Haydarpasa Numune Medical Journal, 2023, Vol 6, Issue 3, p270
- ISSN
2630-5720
- Publication type
Article
- DOI
10.14744/hnhj.2022.97658