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- Title
Cell proliferation and protein synthesis as initial factors in determination of axial polarity.
- Authors
Flickinger, R. A.
- Abstract
The rate of cell proliferation relative to that of protein synthesis appears to have an initial role in establishment of axial polarities in developing animal embryos. An increase in this ratio leads to anterior or dorsal differentiation, while reduction allows posterior or ventral differentiation in a number of organisms. The role that various growth factors play in the regulation of proliferation and protein synthesis is examined.
- Subjects
CELL polarity; CELL proliferation; PROTEIN synthesis; EMBRYOLOGY
- Publication
Development, Growth & Differentiation, 2001, Vol 43, Issue 3, p223
- ISSN
0012-1592
- Publication type
Article
- DOI
10.1046/j.1440-169X.2001.00567.x