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- Title
Prostate Cancer-Associated Disseminated Intravascular Coagulation with Excessive Fibrinolysis Treated with Degarelix.
- Authors
Ong, Shawn Y.; Taverna, Josephine; Jokerst, Clint; Enzler, Thomas; Hammode, Emad; Rogowitz, Elisa; Green, Myke R.; Babiker, Hani M.
- Abstract
Disseminated intravascular coagulation (DIC) with excessive fibrinolysis (XFL) is a rare and acute life-threatening variant of DIC in patients with prostate cancer. Patients present with coagulopathy, hypofibrinogenemia, and systemic bleeding. We describe a case of DIC XFL caused by prostate cancer (PC) successfully treated with a single injection of degarelix, a gonadotropin-releasing hormone (GnRH) receptor antagonist. This led to prompt control of the patient’s coagulopathy within ten days of treatment. Our case highlights features of this rare and devastating hemorrhagic complication of PC along with a fast-acting and effective therapeutic drug option.
- Subjects
DISSEMINATED intravascular coagulation; PROSTATE cancer treatment; FIBRINOLYSIS; LUTEINIZING hormone releasing hormone receptors; HORMONE therapy; PROSTATE cancer patients
- Publication
Case Reports in Oncological Medicine, 2015, p1
- ISSN
2090-6706
- Publication type
Article
- DOI
10.1155/2015/212543