We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Natural Host Relationships and Genetic Diversity of Rodent-Associated Hantaviruses in Southeastern Brazil.
- Authors
De Sousa, Ricardo Luiz Moro; Moreli, Marcos Lázaro; Borges, Alessandra Abel; Campos, Gelse Mazzoni; Livonesi, Márcia Cristina; Figueiredo, Luiz Tadeu Moraes; Pinto, Aramis Augusto
- Abstract
Objective: Hantaviruses are rodent-borne RNA viruses that have caused hantavirus cardiopulmonary syndrome in several Brazilian regions. In the present study, geographical distribution, seroprevalence, natural host range, and phylogenetic relations of rodent-associated hantaviruses collected from seven counties of Southeastern Brazil were evaluated. Methods: ELISA, RT-PCR and phylogenetic analysis were used in this study. Results: Antibodies to hantavirus were detected in Bolomys lasiurus, Akodon sp. and Oligoryzomys sp., performing an overall seroprevalence of 5.17%. All seropositive rodents were associated with grasslands or woods surrounded by sugar cane fields. Phylogenetic analysis of partial S- and M-segment sequences showed that viral sequences isolated from B. lasiurus specimens clustered with Araraquara virus. However, a sequence from Akodon sp. shared 100% similarity with Argentinian/Chilean viruses based on the partial S-segment amino acid sequence. Conclusion: These results indicate that there are associations between rodent reservoirs and hantaviruses in some regions of Southeastern Brazil, and suggest the existence of additional hantavirus genetic diversity and host ecology in these areas. Copyright © 2008 S. Karger AG, Basel
- Subjects
BRAZIL; HANTAVIRUSES; VIRUSES; MICROORGANISMS; CARDIOPULMONARY system; GENETICS
- Publication
Intervirology, 2008, Vol 51, Issue 4, p299
- ISSN
0300-5526
- Publication type
Article
- DOI
10.1159/000171818