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- Title
Isolation of Aleutian Disease Virus of Mink in Cell Culture.
- Authors
Porter, David D.; Larsen, Austin E.; Cox, Nancy A.; Porter, Helen G.; Suffin, Stephen C.
- Abstract
Aleutian disease virus, the causative agent of a persistent infection in mink, was isolated in a continuous line of feline renal cells when the cultures were maintained at reduced temperature (31.8°). After serial in vitro passage of the virus at this temperature it had an optimum replication temperature of 37°. An immunofluorescence focus assay was found to be suitable for virus quantitation. The cultured virus reproduced Aleutian disease in mink, and the virus could be reisolated from the mink 10-180 days after inoculation. The properties of the virus suggest that it is a member of the parvovirus group. Copyright © 1977 S. Karger AG, Basel
- Publication
Intervirology, 1977, Vol 8, Issue 3, p129
- ISSN
0300-5526
- Publication type
Article
- DOI
10.1159/000148888