We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hyperparathyroidism and Vitamin D Deficiency after Laparoscopic Gastric Bypass.
- Authors
Clements, Ronald H.; Yellumahanthi, Kishore; Wesley, Mary; Ballem, Naveen; Bland, Kirby I.
- Abstract
Hyperparathyroidism (HPT) can occur after gastric bypass because of the alteration in vitamin D and calcium absorption. Adequate serum vitamin D concentrations have not been clearly defined in this patient population. Vitamin D (Vit D) and parathyroid hormone (PTH) were assessed 1 year after laparoscopic gastric bypass (LGB). The prevalence of HPT and Vit D deficiency were determined and their association was evaluated using Fisher's exact test. Ninety-three patients (aged 44 ± 1.1 years, 49.6 ± 0.67 kg/m² body mass index, 79.6% female, 69.6% white) were evaluated. The prevalence of Vit D deficiency (less than 20 ng/mL) and HPT (greater than 65 pg/mL) was 23.6 per cent (n = 22) and 25.7 per cent (n = 28), respectively. Among patients with HPT, only eight of 28 (28.6%) had Vit D deficiency, and of those with Vit D deficiency, only eight of 22 (36.4%) had HPT. There was a weak inverse correlation (r = -0.37) between PTH and Vit D. Blacks are at higher risk for Vit D deficiency. There was no significant association between Vit D deficiency and HPT, Vii D deficiency and Roux limb length, or HPT and Roux limb length. After LGB, Vit D deficiency and hyperparathyroidism occur commonly. Body mass index and Roux limb length are not associated with these two conditions, but racial differences do exist. There is a weak inverse correlation between Vit D and PTH. Further research is needed to elucidate the causes, treatments, and significance of HPT after LGB.
- Subjects
HYPERPARATHYROIDISM; VITAMIN D deficiency; LAPAROSCOPIC surgery; GASTRIC bypass; CALCIUM in the body
- Publication
American Surgeon, 2008, Vol 74, Issue 6, p469
- ISSN
0003-1348
- Publication type
Article
- DOI
10.1177/000313480807400603