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- Title
Chemical virology: Packing polymers in protein cages.
- Authors
Cornelissen, Jeroen J. L. M.
- Abstract
The article discusses a study on packing polymers in protein cages. It states that biomacromolecules with synthetic polymers is a rewarding strategy to obtain hybrids that combine the properties of enzyme clusters and viruses. It says that one of the reason that protein cages have attracted interest is the high degree of ordering which is an exact number of proteins assemble with cubic symmetry. It adds that Trevor Douglas and colleagues selected a virus-like particle (VLP) that can be transformed in expanded form, a swollen form of the capsule that are required for capsid formation.
- Subjects
PROTEIN research; POLYMERS; VIRUSES; VIRUS-like particles; MACROMOLECULES; HYBRID enzymes; BACTERIAL capsules; CAPSIDS; DOUGLAS, Trevor
- Publication
Nature Chemistry, 2012, Vol 4, Issue 10, p775
- ISSN
1755-4330
- Publication type
Article
- DOI
10.1038/nchem.1462