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- Title
Model of traumatic spinal cord injury in Macaca fascicularis: similarity of experimental lesions created by epidural catheter to human spinal cord injury.
- Authors
Nesathurai, Shanker; Graham, W. Andrew; Mansfield, Keith; Magill, David; Sehgal, Prabhat; Westmoreland, Susan V.; Prusty, Somnath; Rosene, Doug L.; Sledge, John B.
- Abstract
The article shows that experimental lesions that appear to be histologically similar to human traumatic spinal cord injury at early time points post-injury can be created with a custom-designed epidural catheter. The goal is to create a small selective lesion that partially disconnects the upper motor neuron supply from the lower motor neuron pools that are responsible for tail movement. The catheter will be positioned in the spinal cord to know the optimal location to induce the lesion.
- Subjects
SPINAL cord injuries; CATHETERS; HISTOLOGY; EMOTIONAL trauma; MOTOR neurons
- Publication
Journal of Medical Primatology, 2006, Vol 35, Issue 6, p401
- ISSN
0047-2565
- Publication type
Article
- DOI
10.1111/j.1600-0684.2006.00162.x