We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Association of microalbuminuria with left ventricular diastolic dysfunction in type 2 diabetes mellitus.
- Authors
Nadagoudar, Meghana; Singh, V. P.; Kalra, Ravi; Lodha, Piyush; Singh, Karan
- Abstract
Background: Diabetes mellitus is an important independent risk factor for the development of cardiovascular and renal disease which has been the cause of death in majority of the diabetic population. Albuminuria has been shown to predict cardiovascular morbidity and mortality in diabetics. Objective: The purpose of this study was to correlate microalbuminuria and left ventricular diastolic dysfunction (earliest manifestation of heart disease) in type 2 diabetes mellitus to aid in subclinical diagnosis, risk stratification, and prompt management of cardiovascular disease in diabetic patients. Methods: This study assessed the incidence of left ventricular diastolic dysfunction (LVDD) using echocardiography and its correlation with microalbuminuria and with other parameters like age, gender, BMI, duration of diabetes mellitus, and glycosylated hemoglobin in 90 normotensive, type 2 diabetic patients in a tertiary care hospital in Western India. Results: The prevalence of LVDD in our study is 59% (n = 53). The mean age of the study subjects was 60.7 years. Out of 59 subjects with BMI ≥ 25 kg/m2, diastolic dysfunction was seen in 31 patients. The mean duration of diabetes mellitus in our study is 11.5 years. Good glycemic control, i.e., HbA1c ≤ 7.0, was seen in 13 patients with LVDD. Out of 53 subjects with LVDD, 48 (90.5%) subjects had microalbuminuria. Conclusion: There is a significant correlation between microalbuminuria and LVDD in type 2 diabetes mellitus, independent of other parameters studied (age, sex, BMI, glycemic control, and duration of diabetes).
- Subjects
INDIA; RISK assessment; ALBUMINURIA; GLYCOSYLATED hemoglobin; DISEASE duration; GLYCEMIC control; TERTIARY care; TYPE 2 diabetes; ALBUMINS; LEFT ventricular dysfunction; ECHOCARDIOGRAPHY; DISEASE risk factors; DISEASE complications
- Publication
International Journal of Diabetes in Developing Countries, 2024, Vol 44, Issue 2, p265
- ISSN
0973-3930
- Publication type
Article
- DOI
10.1007/s13410-023-01234-z