We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Peripheral expression of inflammatory markers in overweight female adolescents and eutrophic female adolescents with a high percentage of body fat.
- Authors
Carvalho, Gisele Queiroz; Pereira, Patr�xED;cia Feliciano; Serrano, Hiara Miguel Stancioli; do Carmo Castro Franceschini, Sylvia; Oliveira de Paula, Sérgio; Priore, Silvia Eloiza; do Carmo Gouveia Peluzio, Maria
- Abstract
The objective of this study was to evaluate the peripheral expression of inflammatory markers in adolescents with different nutritional status and its correlation with parameters of the metabolic syndrome. Seventy-two female postpubescent adolescents were divided into 3 groups: eutrophic (Co), eutrophic with a high body fat percentage (HBF), and overweight (OW). Data related to the parameters of the metabolic syndrome and the peripheral expression of tumour necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 were evaluated. Higher values of glycemia and insulin resistance were found in the HBF group than in the Co group. No differences related to the peripheral expression of the cytokines were found among the groups. In the HBF group, a positive correlation was observed between TNF-α and IL-6, IL-10 and the proinflammatory cytokines, and IL-6 and glycemia. In the OW group, a positive correlation was found between IL-6 and triglycerides. Adolescents with normal weight but body fat excess present a metabolic profile and body composition similar to those of overweight adolescents. This suggests that these adolescents have a risk of developing cardiovascular diseases similar to that of overweight adolescents. The positive correlation between IL-10 and TNF-α and IL-6 suggests an attempt to inhibit the production of these cytokines by IL-10.
- Subjects
BRAZIL; INSULIN resistance; BODY composition; ANTHROPOMETRY; BIOMARKERS; BLOOD pressure measurement; CHOLESTEROL; COMPUTER software; CYTOKINES; DIET; EPIDEMIOLOGICAL research; BIOELECTRIC impedance; INFLAMMATION; INTERLEUKINS; MATHEMATICS; NONPARAMETRIC statistics; NUTRITIONAL requirements; POLYMERASE chain reaction; RESEARCH funding; STATISTICS; ADOLESCENT health; TRIGLYCERIDES; TUMOR necrosis factors; U-statistics; WOMEN'S health; ADOLESCENT nutrition; DATA analysis; METABOLIC syndrome; BODY mass index; CROSS-sectional method; REVERSE transcriptase polymerase chain reaction; ADOLESCENCE; BLOOD; DIAGNOSIS
- Publication
Applied Physiology, Nutrition & Metabolism, 2010, Vol 35, Issue 4, p464
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/H10-033