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- Title
Comparative Study of Laparoscopic Versus Open Liver Resection in Gallbladder Cancer.
- Authors
D'Silva, Mizelle; Han, Ho-Seong; Yoon, Yoo-Seok; Cho, Jai Young
- Abstract
Background: In recent decades, laparoscopic liver resection (LLR) has been gradually adopted at high-volume centers, particularly for hepatocellular carcinoma and liver metastasis. However, LLR in patients with gallbladder cancer (GBC) is a controversial issue, and there are few studies of LLR for GBC. Our aim was to compare the outcomes of patients who underwent laparoscopic or open liver resection for GBC. Materials and Methods: All patients admitted with stage II or III GBC requiring liver resection, together with cholecystectomy and lymphadenectomy, were analyzed retrospectively. Patients with thickness of the resected liver specimen >2 cm in pathology reports were included. Results: A total of 56 patients with stage II or III GBC were included in this study; 23 (41.1%) underwent laparoscopic surgery and 33 (58.9%) underwent open surgery. Propensity score matching was performed using a 1:1 matching scheme. After matching, 12 patients were included in each group. The preoperative characteristics of both groups were similar, as were the operative times (laparoscopic versus open group: 237.5 minutes versus 272.5 minutes, respectively; P = .319) and blood loss (300 mL versus 275 mL, respectively; P = .307). The laparoscopic group had a significantly shorter postoperative hospital stay than the open surgery group (4.5 days versus 8 days, respectively; P = .012). There were no major complications in either group. There was no difference between the groups in the number of lymph nodes harvested at surgery (P = .910). There were no differences between the two groups in disease-free (P = .503) or overall (P = .719) survival. Conclusion: LLR extended to GBC provides outcomes similar to those of open surgery. With increasing experience, LLR can be a viable alternative to open surgery for GBC.
- Subjects
GALLBLADDER cancer; LIVER surgery; LYMPH node surgery; ONCOLOGIC surgery; LAPAROSCOPIC surgery; PROPENSITY score matching; LENGTH of stay in hospitals; GALLBLADDER tumors; LIVER tumors; RETROSPECTIVE studies; SURGICAL complications; LAPAROSCOPY; HEPATOCELLULAR carcinoma; HEPATECTOMY; PROBABILITY theory
- Publication
Journal of Laparoendoscopic & Advanced Surgical Techniques, 2022, Vol 32, Issue 8, p854
- ISSN
1092-6429
- Publication type
journal article
- DOI
10.1089/lap.2021.0670