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- Title
Prevalence and patient characteristics associated with pleural tuberculosis in Nigeria.
- Authors
Adewole, Olufemi O.; Erhabor, Greg E.; Ogunrombi, Akinwumi B.; Awopeju, Fehintola A.
- Abstract
Background: Tuberculosis is a leading cause of mortality worldwide, with a growing death rate. The pleural space is a common extrapulmonary site of involvement. The aim of this paper is to document prevalence and types of pleural involvement in pulmonary tuberculosis and patient characteristics associated with its occurrence. Methodology: The study was conducted in a hospital outpatient clinic in which consecutive patients with pulmonary tuberculosis (PTB) or suspects were recruited and studied for the presence of co existing pleural disease or involvement (PD). Results: Of 100 patients studied, eighty-two (82%) had PTB alone and six (6%) patients had PD. Pleural effusion was responsible for the majority of the cases, accounting for 67% of PD. There was no case of empyema. Mean age between patients with PTB and PTB/PD was similar. On univariate analysis, patients with PD had a shorter duration of symptoms and increased reporting of fever (p value = .0.02) and were also different from those with only PTB in HIV seropositivity and sputum smear from AFB (p value = 0.02 and 0.00 respectively). However, after adjustment for multiple comparisons using the Bonferroni test, the only significant difference between them was in the HIV seropositivity rate (p value < 0.012). Conclusion: Less than one tenth of patients with PTB have co-existing and involvement of the pleural space. Pleural involvement is associated with HIV.
- Subjects
NIGERIA; TUBERCULOSIS; DEATH rate; MYCOBACTERIAL diseases; HIV infections; OUTPATIENT medical care
- Publication
Journal of Infection in Developing Countries, 2010, Vol 4, Issue 4, p213
- ISSN
2036-6590
- Publication type
Article
- DOI
10.3855/jidc.699