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- Title
Benign dermoscopic features in melanoma.
- Authors
Di Stefani, A.; Massone, C.; Soyer, H.P.; Zalaudek, I.; Argenziano, G.; Arzberger, E.; Lozzi, G.P.; Chimenti, S.; Hofmann ‐ Wellenhof, R.
- Abstract
Background Various dermoscopic features are usually associated with benign melanocytic lesions. Our objective was to determine frequency and extension of benign dermoscopic features ( BDF) in melanoma. Methods Retrospective review of dermoscopic images of a consecutive series of 516 histopathologically proven melanomas collected in 6 years in Graz. Correlation of BDF with mean Breslow thickness, with presence/absence of associated benign nevus component and with the pre-operative clinico-dermoscopic diagnosis, as reported on the original histopathologic reports. Results In addition to melanoma specific criteria, 42% of melanomas showed BDF. In 12.3% cases, the benign features occupied more than the half of the lesion. The BDF typical pigment network, homogeneous pattern and regular globules/cobblestone pattern had the highest frequency. BDF were associated with relatively thinner melanomas (mean Breslow thickness of 0.51 mm). The presence of BDF was observed in 67.1% of histopathologically documented nevus-associated melanoma and in 35.7% of melanoma de novo. A pre-operative clinico-dermoscopic diagnosis of melanoma was achieved in only 54.1% of cases displaying BDF. Conclusion A significant proportion of melanomas may exhibit BDF. Clinicians should be aware of the presence of BDF in melanoma as possible diagnostic pitfall.
- Subjects
MELANOMA; PRECANCEROUS conditions; HISTOPATHOLOGY; NEVUS; DISEASE prevalence; CANCER risk factors
- Publication
Journal of the European Academy of Dermatology & Venereology, 2014, Vol 28, Issue 6, p799
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/jdv.12192