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- Title
Muscle-building supplement use and increased risk of testicular germ cell cancer in men from Connecticut and Massachusetts.
- Authors
Li, N; Hauser, R; Holford, T; Zhu, Y; Zhang, Y; Bassig, B A; Honig, S; Chen, C; Boyle, P; Dai, M; Schwartz, S M; Morey, P; Sayward, H; Hu, Z; Shen, H; Gomery, P; Zheng, T
- Abstract
Background:No analytic epidemiological study has examined the relationship between use of muscle-building supplements (MBSs) and testicular germ cell cancer (TGCC) risk.Methods:We conducted a population-based case-control study including 356 TGCC cases and 513 controls from Connecticut and Massachusetts.Results:The odds ratio (OR) for ever use of MBSs in relation to risk of TGCC was significantly elevated (OR=1.65, 95% confidence interval (CI): 1.11-2.46). The associations were significantly stronger among early users, men with more types of MBSs used, and longer periods of use.Conclusions:MBS use is a potentially modifiable risk factor that may be associated with TGCC.
- Subjects
MASSACHUSETTS; CONNECTICUT; GERM cell tumors; CANCER risk factors; TESTICULAR cancer; CRYPTORCHISM; EPIDEMIOLOGY; DOSE-response relationship in biochemistry; TUMOR risk factors
- Publication
British Journal of Cancer, 2015, Vol 112, Issue 7, p1247
- ISSN
0007-0920
- Publication type
Article
- DOI
10.1038/bjc.2015.26