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- Title
NO may prompt calcium leakage in dystrophic muscle.
- Authors
Tidball, James G.; Villalta, S. Armando
- Abstract
The article presents a study which examines the new options for therapeutic interventions of Duchene muscular dystrophy (DMD). It states that the cause of DMD is the mutation in the gene that encodes dystrophin which is a low-prevalence, member-associated, cytoskeletal protein in the muscle. Bellinger and colleagues introduced a mechanism which may associate muscle inflammation with wasting and death of muscle in the standard model of DMD, mdx mouse.
- Subjects
MUSCULAR dystrophy treatment; NEUROMUSCULAR diseases; DYSTROPHIN; MEMBRANE proteins; MUSCLE proteins
- Publication
Nature Medicine, 2009, Vol 15, Issue 3, p243
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm0309-243