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- Title
Human Caliciviruses as a Cause of Severe Gastroenteritis in Peruvian Children.
- Authors
Parashar, Umesh D.; Jin-fen Li; Cama, Rosa; DeZalia, Mark; Monroe, Stephan S.; Taylor, David N.; Figueroa, Dante; Gilman, Robert H.; Glass, Roger I.
- Abstract
To define the role of human caliciviruses (HuCVs) in severe childhood gastroenteritis, fecal and paired serum samples from 233 Peruvian children hospitalized with gastroenteriris (case patients) and fecal samples from 248 control subjects were evaluated. Overall, 128 case patients (55%) demonstrated HuCV infection by either fecal (n = 81 [35%]) or serological (n = 96 [41%]) testing. HuCVs were more prevalent in fecal samples from case patients than those from control subjects (35% vs. 13%; P< .001). HuCV infection was more prevalent among case patients without another pathogen than in those who had a coinfecting pathogen (77% [40/52] vs. 49% [88/181]; P< .001). HuCVs appear to be an important cause of gastroenteritis in Peruvian children.
- Subjects
PERU; GASTROENTERITIS in children; RNA viruses; COMMUNICABLE diseases; MEDICAL research; PROGNOSIS; CHILDREN'S health
- Publication
Journal of Infectious Diseases, 2004, Vol 190, Issue 6, p1088
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/423324