We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Characterization of Staphylococcus aureus isolated from patients with burns in a regional burn center, Southeastern China.
- Authors
Chen, Kaisen; Lin, Shirong; Li, Peiqun; Song, Qiuyue; Luo, Dong; Liu, Tao; Zeng, Lingbing; Zhang, Wei
- Abstract
<bold>Background: </bold>S.aureus is a predominant pathogen that causes infection in critically ill patients, but little information exists regarding the characterization of S. aureus from different sources in burn patients in southeastern China.<bold>Methods: </bold>We enrolled 125 patients with S. aureus infection in burns center between Jan 2014 and Dec 2015. S. aureus isolates were characterized by antimicrobial susceptibility test, toxin gene detection, and molecular typing with multilocus sequence type, staphylococcal protein A (spa) type, and staphylococcal cassette chromosome mec (SCCmec) type.<bold>Results: </bold>Sixty-eight MRSA were isolated from SSTI and 31 from non-SSTI patients, respectively. Overall, the drug-resistant ability of S. aureus isolated from SSTI was higher than that from non-SSTI groups. SCCmecIII-CC239-t030 was the most common clone (38 from SSTIs, and 8 from non-SSTIs). Seg was the most common enterotoxin gene (21 from SSTIs and 33 from non-SSTIs). Isolates from SSTIs was more likely to carry seb (P = 0.04), while those from non-SSTIs tended to carry sea and seg (P = 0.002 and 0.01, respectively). Although isolates carried four hemolysin genes, there was no significant difference between them (P > 0.05).<bold>Conclusion: </bold>SCCmecIII-CC239-t030 was the most common clone in Jiangxi burns center, China. The molecular characterization of S. aureus was quite different between SSTI and non-SSTI groups.
- Subjects
CHINA; STAPHYLOCOCCUS aureus; BURN patients; MICROBIAL sensitivity tests; STAPHYLOCOCCAL protein A; ENTEROTOXIN genetics; MOLECULAR epidemiology; BURNS &; scalds complications; BURN care units; BURNS &; scalds; COMMUNICABLE diseases; COMPARATIVE studies; DRUG resistance in microorganisms; RESEARCH methodology; MEDICAL cooperation; RESEARCH; SKIN diseases; STAPHYLOCOCCAL diseases; TOXINS; EVALUATION research; METHICILLIN-resistant staphylococcus aureus; SEQUENCE analysis
- Publication
BMC Infectious Diseases, 2018, Vol 18, p1
- ISSN
1471-2334
- Publication type
journal article
- DOI
10.1186/s12879-018-2955-6