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- Title
Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance.
- Authors
Goire, Namraj; Lahra, Monica M.; Chen, Marcus; Donovan, Basil; Fairley, Christopher K.; Guy, Rebecca; Kaldor, John; Regan, David; Ward, James; Nissen, Michael D.; Sloots, Theo P.; Whiley, David M.
- Abstract
The best available data indicate that the world is heading towards a pandemic of extensively drug-resistant Neisseria gonorrhoeae. At the same time, clinical microbiology laboratories have moved away from using culture-based methods to diagnose gonorrhoea, thus undermining our ability to detect antimicrobial resistance (AMR) using current technologies. In this Opinion article, we discuss the problem of N. gonorrhoeae AMR, particularly emerging resistance to the cephalosporin ceftriaxone, outline current concerns about the surveillance of N. gonorrhoeae AMR and propose the use of molecular methods on a large scale to systematically enhance surveillance.
- Subjects
DRUG resistance in bacteria; ANTI-infective agents; GONORRHEA diagnosis; NEISSERIA gonorrhoeae; CEPHALOSPORINS; MOLECULAR biology
- Publication
Nature Reviews Microbiology, 2014, Vol 12, Issue 3, p223
- ISSN
1740-1526
- Publication type
Article
- DOI
10.1038/nrmicro3217