We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Epidemiology of Pediatric Cardiomyopathy in a Mediterranean Population.
- Authors
Bagkaki, Alena; Parthenakis, Fragiskos; Chlouverakis, Gregory; Anastasakis, Aris; Papagiannis, Ioannis; Galanakis, Emmanouil; Germanakis, Ioannis
- Abstract
Background. Our knowledge regarding the epidemiology of pediatric cardiomyopathy is based on large national population studies reporting an annual incidence of 1 case per 100,000 children, with a higher incidence observed in infancy and among selected populations. The aim here is to document the epidemiology of pediatric cardiomyopathy in a Mediterranean population. Methods. Children younger than 18 years of age living on the Mediterranean island of Crete, Greece, who have been evaluated since the establishment of tertiary pediatric cardiology services (2002–2022) were included in this retrospective study. Results. A total of 40 children were included, corresponding to an average annual incidence of pediatric cardiomyopathy of 1.59 cases (95% CI: 1.4–2.3) and a prevalence of 26 cases per 100,000 children. In decreasing order of frequency, most cases corresponded to dilated (50%), followed by hypertrophic (42.5%), arrhythmogenic (5%), and restrictive (2.5%) cardiomyopathy. An etiology was identified in 40%, including a genetic diagnosis in 22.5%. Conclusions. The incidence of pediatric cardiomyopathy in the Mediterranean island of Crete is higher compared with that reported previously for other Caucasian populations. Further study is needed to investigate the exact prevalence and specific genetic factors associated with the epidemiology of pediatric cardiomyopathy in Mediterranean populations.
- Subjects
ISLANDS of the Mediterranean; GREECE; HEART murmurs; CARDIOMYOPATHIES; VENTRICULAR ejection fraction; NOONAN syndrome; SEX distribution; FISHER exact test; PROBABILITY theory; SYNCOPE; RETROSPECTIVE studies; DILATED cardiomyopathy; CARDIAC hypertrophy; AGE distribution; HEART failure; TREATMENT effectiveness; DESCRIPTIVE statistics; RACE; AGE factors in disease; GLYCOGEN storage disease; HEART transplantation; MEDICAL records; ACQUISITION of data; SEIZURES (Medicine); IMPLANTABLE cardioverter-defibrillators; DISEASE complications; CONFIDENCE intervals; CARDIAC arrest; FATTY acids; MEDITERRANEAN peoples; ECHOCARDIOGRAPHY; PHENOTYPES; GENETIC testing
- Publication
Children, 2024, Vol 11, Issue 6, p732
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children11060732