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- Title
Predictors of anxiety and depression in people with colorectal cancer.
- Authors
Gray, Nicola; Hall, Susan; Browne, Susan; Johnston, Marie; Lee, Amanda; Macleod, Una; Mitchell, Elizabeth; Samuel, Leslie; Campbell, Neil
- Abstract
Background: People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these. Methods: Four hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Case-note-identified disease, treatment and co-morbidity data were recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness. Results: Self-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness ( p = 0.043), as did poorer self-reported cognitive functioning ( p = 0.001), dyspnoea ( p = 0.015) or diarrhoea ( p = 0.021), reporting a high negative life and emotional impact ( p < 0.001) and having difficulties with finance ( p = 0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness ( p = 0.007), as did poorer physical ( p = 0.007), cognitive ( p < 0.001) and social ( p < 0.001) functioning, having constipation ( p = 0.011), reporting a high negative life and emotional impact ( p < 0.001), having difficulties with personal care ( p = 0.022) and communicating with others ( p = 0.014). Conclusion: Levels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention.
- Subjects
MENTAL depression; ANXIETY; COLON cancer patients; PREDICTION theory; QUESTIONNAIRES; LOGISTIC regression analysis
- Publication
Supportive Care in Cancer, 2014, Vol 22, Issue 2, p307
- ISSN
0941-4355
- Publication type
Article
- DOI
10.1007/s00520-013-1963-8