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- Title
Pyloric stenosis: an enigma more than a century after the first successful treatment.
- Authors
El-Gohary, Yousef; Abdelhafeez, Abdelhafeez; Paton, Elizabeth; Gosain, Ankush; Murphy, Andrew J.
- Abstract
Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood. We review the diagnosis and treatment of this condition with an emphasis on the evolution of surgical techniques that led to laparoscopic pyloromyotomy, the most frequently performed technique for HPS today. In addition, we review key developments in the understanding of HPS etiology and treatment, including the postulated etiology of work-induced hypertrophy of the pylorus, its association with prokinetic macrolide antibiotics, and the emerging role of atropine sulfate as a medical treatment for HPS or a rescue treatment for incomplete myotomy.
- Subjects
PYLORIC stenosis; PEDIATRICS; ETIOLOGY of diseases; MACROLIDE antibiotics; DIAGNOSIS; PATIENTS; THERAPEUTICS
- Publication
Pediatric Surgery International, 2018, Vol 34, Issue 1, p21
- ISSN
0179-0358
- Publication type
journal article
- DOI
10.1007/s00383-017-4196-y